Mata grabbed a double as United beat the Reds 2-1 at Anfield.
The result has put United in the driving seat for a Champions League spot as they are five points clear of Brendan Rodgers' men in fourth spot in the Premier League table.
Mata, who was named Man of the Match, told Sky Sports: "I think it's my best game in a United shirt, yes.
"It's a massive game, probably the biggest in English football, so to score two goals is great for me.
GETTY
Juan Mata celebrates after scoring a stunning second goal
I think it's my best game in a United shirt, yes
Juan Mata
"It was important for me. The last few months I've not had the best moment. It is the manager who decides but I'm happy today."
Mata also thought his second goal, an acrobatic effort, was arguably his favourite strike for the Red Devils.
He added: "The second goal has to be up there with my best. After Steven Gerrard was sent off we needed a second goal because they pushed us to the end."
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